骨膜蛋白(POSTN)單克隆抗體
Monoclonal Antibody to Periostin (POSTN)
OSF-2; PDLPOSTN; PN; Osteoblast Specific Factor 2
- 編號UMAH339Hu21
- 物種Homo sapiens (Human，人) 相同的名稱，不同的物種。
- 來源單抗制備
- 宿主小鼠
- 效價(克隆號)C6
- Ig亞型 IgG1 Kappa
- 純化方式蛋白A + 蛋白G親和純化
- 標記物無標記物
- 免疫原 RPH339Hu01-骨膜蛋白(POSTN)重組蛋白
- 緩沖液成份0.01M 磷酸鹽緩沖液（pH7.4，containing 0.05% Proclin-300，50% glycerol）
- 性狀液體
- 濃度1mg/ml
- 且適物種Rattus norvegicus (Rat，大鼠)
- 應(yīng)用WB; ICC/IF
如果抗體需用于流式細胞術(shù)，請參見流式抗體。 - 下載 英文說明書 中文說明書
- 規(guī)格 20μl100μl 200μl 1ml 10ml
- 價格 ¥ 333 ¥ 777 ¥ 1110 ¥ 2775 ¥ 11100
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產(chǎn)品包裝(模擬)
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產(chǎn)品包裝(模擬)
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IHC圖
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AF488 staining on IF;<br/>Sample: Hela cell<br/>Primary Ab: 30μg/mL Mouse Anti-Human POSTN Antibody<br/>Second Ab: 2μg/mL AF488-Linked Caprine Anti-Mouse IgG Polyclonal Antibody<br/>(Catalog: SAA544Mu11)
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Figure. Western Blot; Sample: Recombinant POSTN, Human.
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Western Blot; Sample: Lane1: Human Placenta lysate; Lane2: Human Lung lysate; Lane3: Rat Lung lysate<br/>Primary Ab: 3μg/mL Mouse Anti-Human POSTN Antibody<br/>Second Ab: 0.2μg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody<br/>(Catalog: SAA544Mu19)
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通過ISO 9001、ISO 13485質(zhì)量體系認證
特異性
該抗體是針對POSTN的小鼠單克隆抗體。在免疫組織化學(xué)染色和免疫印跡實驗中能識別POSTN。
用法
Western blotting: 0.01-3μg/mL;
Immunocytochemistry: 5-30μg/mL;
Optimal working dilutions must be determined by end user.
儲存
經(jīng)常使用則4°C保存。-20°C保存不超過兩年。避免反復(fù)凍融。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當?shù)臈l件下存儲，損失率低于5%。
贈品
增值服務(wù)
相關(guān)產(chǎn)品
| 編號 | 適用物種：Homo sapiens (Human，人) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| URPH339Hu03 | 骨膜蛋白(POSTN)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| URPH339Hu01 | 骨膜蛋白(POSTN)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| URPH339Hu02 | 骨膜蛋白(POSTN)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| UPAH339Hu01 | 骨膜蛋白(POSTN)多克隆抗體 | WB; IHC |
| UPAH339Hu02 | 骨膜蛋白(POSTN)多克隆抗體 | WB; IHC; ICC; IP. |
| UPAH339Hu03 | 骨膜蛋白(POSTN)多克隆抗體 | IHC |
| UFAH339Hu01 | 抗骨膜蛋白(POSTN)多克隆抗體 | FCM |
| ULAH339Hu71 | 骨膜蛋白(POSTN)多克隆抗體(生物素標記) | WB; IHC; ICC. |
| UMAH339Hu23 | 骨膜蛋白(POSTN)單克隆抗體 | IHC; ICC/IF |
| UMAH339Hu24 | 骨膜蛋白(POSTN)單克隆抗體 | WB |
| UMAH339Hu21 | 骨膜蛋白(POSTN)單克隆抗體 | WB; ICC/IF |
| UMAH339Hu27 | 骨膜蛋白(POSTN)單克隆抗體 | WB |
| UMAH339Hu29 | 骨膜蛋白(POSTN)單克隆抗體 | ICC/IF |
| UMAH339Hu22 | 骨膜蛋白(POSTN)單克隆抗體 | WB; ICC/IF |
| USEH339Hu | 骨膜蛋白(POSTN)檢測試劑盒(酶聯(lián)免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| ULMH339Hu | 骨膜蛋白(POSTN)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻
| 雜志 | 參考文獻 |
| Blood | Circulating Periostin Is Elevated In Patients With Hemoglobinopathies and Correlates With Bone Mineral Density In Double Heterozygous Sickle-Cell/Beta-Thalassemia Patients; A Novel Marker Of Bone Strength? [Bloodjournal: Source] |
| The Journal of Clinical Endocrinology & Metabolism | Serum periostin is associated with fracture risk in postmenopausal women: a 7 years prospective analysis of the OFELY study [Pubmed: 24628551] |
| J Clin Endocrinol Metab. | Serum Periostin Is Associated With Fracture Risk in Postmenopausal Women: A 7-Year Prospective Analysis of the OFELY Study [Pubmed:24628551] |
| Rheumatology (Oxford). | Circulating periostin levels in patients with AS: association with clinical and radiographic variables, inflammatory markers and molecules involved in bone formation [Pubmed:25349442] |
| Journal of Periodontal Research | Assessment of periostin levels in serum and gingival crevicular fluid of patients with periodontal disease [Pubmed:25529858] |
| 新醫(yī)學(xué) | 血清內(nèi)脂素水平與多囊卵巢綜合征的相關(guān)性研究 [Xinyixue:Source] |
| Osteoarthritis | Serum periostin is associated with prevalent knee osteoarthritis and disease incidence/progression in women: the OFELY study [PubMed: 26072384] |
| Endocrine | Serum periostin is a potential biomarker for non-alcoholic fatty liver disease: a case– control study [PubMed: 26362060] |
| Blood?Cancer?Journal | High levels of periostin correlate with increased fracture rate, diffuse MRI pattern, abnormal bone remodeling and advanced disease stage in patients with newly … [pubmed:27716740] |
| Metabolism.? | Low periostin levels in adult patients with Langerhans cell histiocytosis are independently associated with the disease activity. [pubmed:28521873] |
| Osteoporosis International | Circulating periostin levels increase in association with bone density loss and healing progression during the early phase of hip fracture in Chinese older women [pubmed:28382553] |
| Molecular Diagnosis & Therapy | The Utility of Biomarkers in Osteoporosis Management [pubmed:28271451] |
| Journal of Bone and Mineral Research | Cortical and trabecular bone microstructure did not recover at weight-bearing skeletal sites and progressively deteriorated at non-weight-bearing sites during the year following International Space Station missions [doi:10.1002] |
| Clinical Cases in Mineral and Bone Metabolism | Periostin and sclerostin levels in juvenile Paget's disease [pubmed:29263750] |
| Calcified?Tissue?International | Development of a New Immunoassay for Human Cathepsin K-Generated Periostin Fragments as a Serum Biomarker for Cortical Bone [pubmed:28725907] |
| Wiley | Characterization of a sandwich ELISA for the quantification of all human periostin isoforms [pubmed:28493527] |
| International Osteoporosis Foundation and National Osteoporosis Foundation | Interaction between LRP5 and periostin gene polymorphisms on serum periostin levels and cortical bone microstructure [pubmed:29038835] |
| Bone | Effect of age and gender on serum periostin: Relationship to cortical measures, bone turnover and hormones [pubmed:28323143] |
| Clinica Chimica Acta | Association between serum periostin concentrations and outcome after acute spontaneous intracerebral hemorrhage [pubmed:28882488] |
| Clinica Chimica Acta | Serum periostin concentrations and outcomes after severe traumatic brain injury [pubmed:28668564] |
| Tumor Biology | Predictive and prognostic value of serum periostin in advanced non–small cell lung cancer patients receiving chemotherapy [pubmed:28459197] |
| Journal of Bone and Mineral Research | Serum Levels of a Cathepsin-K Generated Periostin Fragment Predict Incident Low-Trauma Fractures in Postmenopausal Women Independently of BMD and FRAX [pubmed:28766739] |
| ОСОБЕННОСТИ СОСТОЯНИЯ ЗДОРОВЬЯ НОВОРОЖДЕННЫХ, РОЖДЕННЫХ ОТ МАТЕРЕЙ С БРОНХИАЛЬНОЙ АСТМОЙ [2017; 62:(4)] | |
| Endocrine | Circulating periostin in patients with nonalcoholic fatty liver disease. [pubmed:27738886] |
| Molecular Medicine Reports | Periostin cross?reacts with the renin?angiotensin system during liver fibrosis development [pubmed:28849131] |
| The Journal of Biological Chemistry | Toll-like receptor 2 deficiency hyperactivates the FoxO1 transcription factor and induces aging-associated cardiac dysfunction in mice [Pubmed:29929978] |
| Calcified?Tissue?International | The C-Terminal Intact Forms of Periostin (iPTN) Are Surrogate Markers for Osteolytic Lesions in Experimental Breast Cancer Bone Metastasis [Pubmed:29916127] |
| Journal of Endocrinological Investigation | Increased serum periostin concentrations are associated with the presence of diabetic retinopathy in patients with type 2 diabetes mellitus [Pubmed:29349642] |
| Wiener klinische Wochenschrift | Rheumatoid arthritis in remission [] |
| Clinical?and Experimental Medicine | Myostatin and other musculoskeletal markers in lung transplant recipients [Pubmed: 30317402] |
| Experimental?and?Clinical?Endocrinology?&?Diabetes | Polycystic Ovary Syndrome is Associated with Elevated Periostin Levels [Pubmed: 30372763] |
| ИСПОЛЬЗОВАНИЕ СЫВОРОТОЧНОГО ПЕРИОСТИНА В КАЧЕСТВЕ МАРКЕРА ОБОСТРЕНИЙ АСТМЫ У ДЕТЕЙ [] | |
| Bone | Tartrate-resistant acid phosphatase 5b, but not periostin, is useful for assessing Paget's disease of bone [Pubmed: 31051316] |
| Journal of Clinical Laboratory Analysis | Identification and diagnostic value of pleural fluid periostin and serum periostin of malignant pleural effusions in patients with non–small‐cell lung cancer [Pubmed: 31268191] |
| Bone | Serum periostin is associated with cancer mortality but not cancer risk in older home-dwelling men: A 8-year prospective analysis of the STRAMBO study [Pubmed: 31812700] |
| FASEB J | Fibronectin rescues aberrant phenotype of endothelial cells lacking either CCM1, CCM2 or CCM3 [Pubmed: 32515053] |
| Journal of Reproductive Immunology | Serum and placental periostin levels in women with early pregnancy loss [Pubmed: 32460058] |
| Annals of Medical Research | Evaluation of periostin levels in gingival crevicular fluid and peri-implant sulcus fluid in patients with periodontal and peri-implanter disease: A cross-sectional?… [] |
| Myostatin and Markers of Bone Metabolism in Dermatomyositis [] | |
| Am J Physiol Heart Circ Physiol | Periostin promotes arterial calcification through PPAR|?-related glucose metabolism reprogramming [33834866] |
| International Journal of Chronic Obstructive Pulmonary Disease | High Blood Eosinophil and YKL-40 Levels, as Well as Low CXCL9 Levels, are Associated with Increased Readmission in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease [33814903] |
| J Bone Oncol | Serum total periostin is an independent marker of overall survival in bone metastases of lung adenocarcinoma [34150488] |
| Rambam Maimonides Med J | The Relationship between Serum Periostin Levels and Neutrophil¨CLymphocyte Ratio with Lesion Localization and Acute Prognosis in Acute Ischemic Stroke [34137680] |
| Rambam Maimonides Medical Journal | First Admission Neutrophil–Lymphocyte Ratio May Indicate Acute Prognosis of Ischemic Stroke [34137680] |
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